Researchers discover a novel pathway that minimizes liver injury during transplantation

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71380login-checkResearchers discover a novel pathway that minimizes liver injury during transplantation

By University of California, Los Angeles

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes. But the features that regulate this protective characteristic remain unknown.

In a study, published online Aug. 2 in Science Translational Medicine, a research team has identified the molecular factors at the root of this protection and shown how using molecular tools and alternative gene splicing can make CEACAM1 more protective, thus reducing organ injury and ultimately improving post-transplant outcomes. Read the full article in Medical Xpress.

713810login-checkResearchers discover a novel pathway that minimizes liver injury during transplantation
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