776800login-checkRude Awakening on Trying to Keep Donor Hearts Usable With Common Hormone Infusions |
— Long-standing practice of levothyroxine supplementation fails in randomized trial
By Nicole Lou
Giving unstable brain-dead heart donors intravenous levothyroxine did not lead to more hearts being transplanted, a randomized trial showed.
In hemodynamically unstable potential donors, administering the thyroid hormone supplement after brain death did not significantly improve donor heart utilization compared with saline placebo, with transplantation rates of 54.9% and 53.2%, respectively (adjusted risk ratio 1.01, 95% CI 0.97-1.07), reported Rajat Dhar, MD, of Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, and colleagues. Read the article in MedPage Today.
776800login-checkRude Awakening on Trying to Keep Donor Hearts Usable With Common Hormone Infusions |